CONN

fcMRI courses

next course Fall 2024 (Sept 16 - Oct 18)

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Resting-state functional connectivity has taken the brain imaging community by storm. Five to ten minutes of MRI data collection from almost any subject or patient can reveal organized systems of activity in the brain that can be used in a wide variety of ways for basic and clinical research, and even to guide non-invasive brain stimulation. 

CONN is one of the most popular software packages for functional connectivity Magnetic Resonance Imaging (fcMRI) analyses of resting state and task fMRI data, with over 6,000 published studies to date using CONN. It is ranked in the top 1% most frequently viewed and downloaded neuroimaging tools in NITRC, and it enjoys a large and active user community, with over 2,000,000 page-views and 14,000 user-support posts.

In this workshop the neuroimaging researcher and lead developer of CONN, Alfonso Nieto-Castanon, brings his exceptional expertise to offer a course covering all aspects of functional connectivity Magnetic Resonance Imaging (fcMRI) analyses in CONN. The course welcomes both new and existing users. It covers basic and advanced features of CONN as well as general topics in functional connectivity analyses. Participants bring their own laptop computers, and classroom presentations are followed by substantial time for questions and exercises using CONN with expert guidance available. Course attendees receive a certificate of completion at the end of the workshop.

This workshop is offered in two different modalities: 

Computational Neuroscience Research Lab
Martinos Center for Biomedical Imaging

The first is virtual through Zoom, where the full course content is presented over a period of 5 weeks, with 3½-hour live classes twice a week. All live Zoom meetings are also recorded and made available to participants to review at any time during the course. There are also optional practice homework assignments and faculty is available during office-hour segments for additional questions or support. 

The second modality is in-person at the Martinos Center for Biomedical Imaging (MGH / Harvard / MIT) in Boston, where an accelerated one-week version of this course is offered. Classes are held Monday to Friday from 9AM to 5PM during a single week. Course content is identical to the virtual/online course except for homework assignments or office-hours, which are not offered in the in-person modality due to time constraints. 

Course contents include essential topics in CONN such as Setup definitions and CONN project design, fMRI preprocessing pipelines, data denoising and quality control, seed-based and ROI-to-ROI connectivity measures, or group-level GLM analyses and inferences, practical discussions covering example clinical applications of functional connectivity analyses, GLM designs for illustrative research questions, batch scripting, and the use of parallelization options in High Performance Computing environments, as well as presentations covering the theory and practice of all specialized functional connectivity methods available in CONN, including generalized Psycho-Physiological Interaction models, temporal modulation analyses, Independent Component Analyses, voxel-to-voxel connectivity measures, network- and cluster- level statistics, graph theory, functional connectivity MultiVariate Pattern Analyses, or dynamic connectivity analyses. 

Use the following links to explore the course contents in more detail, check the schedule, or register to the next CONN workshop.

Principal speaker: Alfonso Nieto-Castanon, Ph.D.

Invited speakers: Robert L. Savoy, Ph.D., Susan Whitfield-Gabrieli, Ph.D., Sheeba Arnold Anteraper, Ph.D.

FAQ

COURSE CONTENTS


WELCOME

CORE 1

Introduction to fcMRI and CONN

CORE 2

Preprocessing functional & anatomical data

CORE 3

Setup: importing all data and study details

CORE 4

Denoising & Quality Control

CORE 5

First-level analyses: SBC, RRC, gPPI & group-ICA

CORE 6

Second-level analyses: GLM, designs & examples

ADVANCED 1

Homework discussion & FC applications

ADVANCED 2

Cluster-level stats & graph theory

ADVANCED 3

Voxel-to-voxel, fc-MVPA & dynamic connectivity

ADVANCED 4

Parallelization options, HPC & scripting

schematic of CONN workshop course content